STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
alsSAcetolactate synthase; Belongs to the TPP enzyme family. (548 aa)    
Predicted Functional Partners:
korA
2-oxoglutarate synthase subunit korA; Function of strongly homologous gene; enzyme.
  
 
 0.953
korB
2-oxoglutarate ferredoxin oxidoreductase beta subunit.
  
 
 0.913
LHA_0442
Acetolactate synthase; Belongs to the TPP enzyme family.
  
  
 
0.912
malS
Putative NAD-dependent malic enzyme 3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 0.874
sfcA
NAD-dependent malic enzyme.
 
 0.871
LHA_2802
Malate oxidoreductase.
  
 0.853
lldD
L-lactate dehydrogenase [cytochrome].
  
 
 0.851
pykA
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.840
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.829
aceE
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.814
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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