STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_1661Homologs of previously reported genes of unknown function. (267 aa)    
Predicted Functional Partners:
yfdZ
Putative aminotransferase, PLP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.866
recJ
Single-stranded-DNA-specific exonuclease recJ.
       0.866
LHA_1659
Homologs of previously reported genes of unknown function.
 
     0.860
LHA_2930
Homologs of previously reported genes of unknown function.
  
     0.762
LHA_2859
Homolog of LvrA protein.
  
     0.749
dusA
tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.
       0.741
LHA_1631
Generic methyl-transferase.
  
     0.709
icmE/dotG
Component of the Dot/Icm secretion system. Major component of a channel; Function of strongly homologous gene; structure.
  
     0.701
LHA_3178
Cysteine protease, papain C1 family.
  
     0.679
IcmF
IcmF protein; Function of strongly homologous gene; factor.
  
     0.678
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
Server load: low (18%) [HD]