recJ protein (Legionella hackeliae) - STRING interaction network

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recJ

Single-stranded-DNA-specific exonuclease recJ. (575 aa)

Predicted Functional Partners:

yfdZ

0.866

LHA_1661

0.866

recQ

0.812

dusA

0.751

LHA_1659

0.748

xseA

0.695

recO

0.693

mutL

0.679

polA

0.675

recG

0.668

Your Current Organism:

Legionella hackeliae

NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LHA_1659	LHA_1661	LHA_1659	LHA_1661	Homologs of previously reported genes of unknown function.	Homologs of previously reported genes of unknown function.	0.860
LHA_1659	dusA	LHA_1659	LHA_1663	Homologs of previously reported genes of unknown function.	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.	0.665
LHA_1659	recJ	LHA_1659	LHA_1662	Homologs of previously reported genes of unknown function.	Single-stranded-DNA-specific exonuclease recJ.	0.748
LHA_1659	yfdZ	LHA_1659	LHA_1660	Homologs of previously reported genes of unknown function.	Putative aminotransferase, PLP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.748
LHA_1661	LHA_1659	LHA_1661	LHA_1659	Homologs of previously reported genes of unknown function.	Homologs of previously reported genes of unknown function.	0.860
LHA_1661	dusA	LHA_1661	LHA_1663	Homologs of previously reported genes of unknown function.	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.	0.741
LHA_1661	recJ	LHA_1661	LHA_1662	Homologs of previously reported genes of unknown function.	Single-stranded-DNA-specific exonuclease recJ.	0.866
LHA_1661	yfdZ	LHA_1661	LHA_1660	Homologs of previously reported genes of unknown function.	Putative aminotransferase, PLP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.866
dusA	LHA_1659	LHA_1663	LHA_1659	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.	Homologs of previously reported genes of unknown function.	0.665
dusA	LHA_1661	LHA_1663	LHA_1661	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.	Homologs of previously reported genes of unknown function.	0.741
dusA	recJ	LHA_1663	LHA_1662	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.	Single-stranded-DNA-specific exonuclease recJ.	0.751
dusA	yfdZ	LHA_1663	LHA_1660	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.	Putative aminotransferase, PLP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.741
mutL	polA	LHA_2729	LHA_0215	DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.886
mutL	recG	LHA_2729	LHA_0653	DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	ATP-dependent DNA helicase recG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.	0.617
mutL	recJ	LHA_2729	LHA_1662	DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	Single-stranded-DNA-specific exonuclease recJ.	0.679
mutL	recO	LHA_2729	LHA_2147	DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	DNA repair protein recO; Involved in DNA repair and RecF pathway recombination.	0.587
mutL	recQ	LHA_2729	LHA_1304	DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	ATP-dependent DNA helicase recQ.	0.820
mutL	xseA	LHA_2729	LHA_2119	DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.	0.656
polA	mutL	LHA_0215	LHA_2729	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	0.886
polA	recG	LHA_0215	LHA_0653	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	ATP-dependent DNA helicase recG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.	0.717