Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LHA_1674EAL domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (497 aa)    
Predicted Functional Partners:
LHA_1069
Sensory box/GGDEF family protein.
 
 0.968
LHA_2650
Diguanylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme;/product='3-ketoacyl-(Acyl-carrier-protein) reductase (fragment)'.
 
 0.940
LHA_3175
Diguanylate cyclase; Function of strongly homologous gene; enzyme.
 
  
 0.928
LHA_3196
Putative regulatory protein (GGDEF, PAS, PAC domains); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.875
coaE
Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
       0.866
LHA_1673
Homologs of previously reported genes of unknown function.
       0.866
LHA_1156
GGDEF domain protein.
  
    0.821
LHA_1530
Diguanylate kinase; Function of strongly homologous gene; enzyme.
  
    0.820
LHA_2758
Response regulator PleD [Includes: Diguanylate cyclase] (fragment).
  
    0.820
LHA_2222
Components of sensory transduction system (fragment).
 
 
 
 0.817
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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