STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_1720Lipase/acylhydrolase family protein; Function of strongly homologous gene; enzyme. (222 aa)    
Predicted Functional Partners:
LHA_3123
Protein of unknown function; No homology to any previously reported sequences.
 
 
 0.687
LHA_0793
Protein of unknown function; No homology to any previously reported sequences.
  
 
 0.604
LHA_1119
Long-chain-fatty-acid--CoA ligase [Beta-ketoacyl synthase active site]; Function of strongly homologous gene; enzyme.
  
  
 0.585
LHA_1995
Beta-ketoacyl synthase (fragment).
  
  
 0.585
LHA_1510
Heparan-alpha-glucosaminide N-acetyltransferase_; Function of strongly homologous gene; enzyme.
  
     0.533
LHA_1719
Protein of unknown function; No homology to any previously reported sequences.
       0.457
LHA_2540
Cellulase; Function of strongly homologous gene; enzyme.
  
 
 0.455
birA
Biotin synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
     
 0.444
LHA_0292
Exported protein of unknown function; No homology to any previously reported sequences.
  
   0.426
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.