STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_1827Histone deacetylase superfamily. (306 aa)    
Predicted Functional Partners:
LHA_2597
Protein of unknown function [coiled-coil domain]; No homology to any previously reported sequences.
    
 0.939
LHA_1146
Homologs of previously reported genes of unknown function.
    
 0.893
LHA_1431
Protein of unknown function [SET domain]; No homology to any previously reported sequences.
  
 0.841
htpG
Chaperone protein htpG; Molecular chaperone. Has ATPase activity.
   
 0.820
LHA_0129
Protein of unknown function; No homology to any previously reported sequences.
   
 0.712
LHA_2342
Homologs of previously reported genes of unknown function.
    
 0.674
LHA_0787
Homologs of previously reported genes of unknown function.
    
 0.601
LHA_1826
Peptidase M28 family protein; Function of strongly homologous gene; enzyme.
   
   0.567
pdxB
Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.
    
 0.561
LHA_2613
Putative D-isomer specific 2-hydroxyacid dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.561
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.