Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ybeZPutative enzyme with nucleoside triphosphate hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (317 aa)    
Predicted Functional Partners:
ybeY
Putative metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.989
ybeX
Putative protein involved in divalent ion export; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
  
 0.953
recO
DNA repair protein recO; Involved in DNA repair and RecF pathway recombination.
  
  
 0.876
cpxA
Sensor histidine kinase CpxA.
  
  
 0.801
cpxR
Transcriptional regulatory protein CpxR.
     
 0.781
clpX
ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
  
    0.727
LHA_1857
Protein of unknown function; No homology to any previously reported sequences.
       0.726
era
GTP-binding protein era homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
 
  
 0.610
LHA_1850
Homologs of previously reported genes of unknown function; Belongs to the pseudouridine synthase RsuA family.
   
   0.580
hfq
Protein hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
   
    0.571
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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