STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_1877Homologs of previously reported genes of unknown function. (96 aa)    
Predicted Functional Partners:
lapB
Conserved protein of unknown function; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
 
   
 0.774
lspL
Type II secretory pathway protein LspL; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
  
     0.654
LHA_2675
Homologs of previously reported genes of unknown function.
  
     0.654
icmJ
IcmJ protein.
  
     0.641
dotA
Component of the Dot/Icm secretion system; Function of strongly homologous gene; membrane component.
  
     0.639
LHA_2708
DotA (fragment).
  
     0.614
xcpU
General secretion pathway protein LspH.
  
     0.607
Ispk
Type II secretory pathway protein; Function of strongly homologous gene; transporter.
 
     0.606
AnkH
Substrate of the Dot/Icm secretion system [ankyrin repeat]; Function of strongly homologous gene; factor.
  
     0.602
icmL/dotI
Component of the Dot/Icm secretion system. Inner membrane protein; Function of strongly homologous gene; membrane component.
  
     0.598
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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