Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LHA_1899Sodium/hydrogen antiporter. (389 aa)    
Predicted Functional Partners:
LHA_1898
Inner membrane protein AmpE.
       0.866
LHA_1229
Na+/H+ antiporter.
 
   
 0.710
LHA_0707
Site specific recombinase, phage integrase.
  
     0.500
LHA_1900
Membrane protein of unknown function; No homology to any previously reported sequences.
       0.476
rlpA
Conserved protein of unknown function; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
       0.461
LHA_1894
GCN5-related N-acetyltransferase.
       0.461
lpdA
Dihydrolipoyl dehydrogenase.
       0.461
aceF
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
       0.461
aceE
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
       0.461
LHA_0596
Homologs of previously reported genes of unknown function.
  
     0.460
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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