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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
htrAProtease DO; Belongs to the peptidase S1C family. (457 aa)    
Predicted Functional Partners:
miaB
(Dimethylallyl)adenosine tRNA methylthiotransferase miaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
       0.841
rluD
Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
       0.841
LHA_1905
Homologs of previously reported genes of unknown function; Belongs to the multicopper oxidase YfiH/RL5 family.
       0.841
LHA_1902
Major facilitator family transporter (Permease).
       0.799
LHA_1849
Putative enhanced entry protein EnhA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
     0.532
LHA_0129
Protein of unknown function; No homology to any previously reported sequences.
   
  0.514
LHA_1119
Long-chain-fatty-acid--CoA ligase [Beta-ketoacyl synthase active site]; Function of strongly homologous gene; enzyme.
  
 0.493
LHA_1995
Beta-ketoacyl synthase (fragment).
  
 0.493
LHA_1901
Protein of unknown function; No homology to any previously reported sequences.
   
   0.463
LHA_1268
Protein of unknown function [ankyrin repeat]; No homology to any previously reported sequences.
  
  0.460
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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