Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LHA_1927Homologs of previously reported genes of unknown function. (472 aa)    
Predicted Functional Partners:
icmE/dotG
Component of the Dot/Icm secretion system. Major component of a channel; Function of strongly homologous gene; structure.
   
 
 0.882
flgG
Flagellar basal-body rod protein flgG; Belongs to the flagella basal body rod proteins family.
  
 
 0.820
rlpA-2
Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
  
  
 0.812
cphA
Cyanophycin synthetase.
     
 0.772
ispZ
Putative intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
       0.726
gloB
Putative hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
       0.723
qseC
Two component sensor kinase.
     
 0.704
amiC
N-acetylmuramoyl-L-alanine amidase.
  
  
 0.702
flgJ
Flagellar biosynthesis protein FlgJ.
     
 0.661
yceG
Putative conserved membrane associated protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
  
  
 0.578
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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