Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LHA_1941AIG2 family protein. (116 aa)    
Predicted Functional Partners:
LHA_1942
Import inner membrane translocase subunit Tim44; Function of strongly homologous gene; membrane component.
 
     0.724
LHA_1119
Long-chain-fatty-acid--CoA ligase [Beta-ketoacyl synthase active site]; Function of strongly homologous gene; enzyme.
   
 
 0.479
LHA_1995
Beta-ketoacyl synthase (fragment).
   
 
 0.479
topA
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
  
  
 0.424
korA
2-oxoglutarate synthase subunit korA; Function of strongly homologous gene; enzyme.
     
 0.422
LHA_1944
Membrane protein of unknown function; No homology to any previously reported sequences.
       0.419
ybbA
Putative transporter subunit: ATP-binding component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
       0.419
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
 
   
 0.418
LHA_0479
Putative hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
   
 0.414
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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