| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LHA_1983 | LHA_1984 | LHA_1983 | LHA_1984 | Putative sidH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | Putative 3'(2'),5'-bisphosphate nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.519 |
| LHA_1983 | LHA_1985 | LHA_1983 | LHA_1985 | Putative sidH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | Ribose-phosphate pyrophosphokinase. | 0.519 |
| LHA_1984 | LHA_1983 | LHA_1984 | LHA_1983 | Putative 3'(2'),5'-bisphosphate nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative sidH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 0.519 |
| LHA_1984 | LHA_1985 | LHA_1984 | LHA_1985 | Putative 3'(2'),5'-bisphosphate nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Ribose-phosphate pyrophosphokinase. | 0.819 |
| LHA_1984 | hisI | LHA_1984 | LHA_1401 | Putative 3'(2'),5'-bisphosphate nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Histidine biosynthesis bifunctional protein hisIE [Includes: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphatase]; In the N-terminal section; belongs to the PRA-CH family. | 0.637 |
| LHA_1984 | orn | LHA_1984 | LHA_2779 | Putative 3'(2'),5'-bisphosphate nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. | 0.582 |
| LHA_1984 | suhB | LHA_1984 | LHA_2205 | Putative 3'(2'),5'-bisphosphate nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Inositol-1-monophosphatase. | 0.459 |
| LHA_1984 | thyA | LHA_1984 | LHA_0193 | Putative 3'(2'),5'-bisphosphate nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.406 |
| LHA_1984 | topA | LHA_1984 | LHA_2889 | Putative 3'(2'),5'-bisphosphate nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] | 0.514 |
| LHA_1985 | LHA_1983 | LHA_1985 | LHA_1983 | Ribose-phosphate pyrophosphokinase. | Putative sidH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 0.519 |
| LHA_1985 | LHA_1984 | LHA_1985 | LHA_1984 | Ribose-phosphate pyrophosphokinase. | Putative 3'(2'),5'-bisphosphate nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.819 |
| LHA_1985 | hisI | LHA_1985 | LHA_1401 | Ribose-phosphate pyrophosphokinase. | Histidine biosynthesis bifunctional protein hisIE [Includes: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphatase]; In the N-terminal section; belongs to the PRA-CH family. | 0.454 |
| hisI | LHA_1984 | LHA_1401 | LHA_1984 | Histidine biosynthesis bifunctional protein hisIE [Includes: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphatase]; In the N-terminal section; belongs to the PRA-CH family. | Putative 3'(2'),5'-bisphosphate nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.637 |
| hisI | LHA_1985 | LHA_1401 | LHA_1985 | Histidine biosynthesis bifunctional protein hisIE [Includes: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphatase]; In the N-terminal section; belongs to the PRA-CH family. | Ribose-phosphate pyrophosphokinase. | 0.454 |
| hisI | suhB | LHA_1401 | LHA_2205 | Histidine biosynthesis bifunctional protein hisIE [Includes: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphatase]; In the N-terminal section; belongs to the PRA-CH family. | Inositol-1-monophosphatase. | 0.595 |
| orn | LHA_1984 | LHA_2779 | LHA_1984 | Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. | Putative 3'(2'),5'-bisphosphate nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.582 |
| suhB | LHA_1984 | LHA_2205 | LHA_1984 | Inositol-1-monophosphatase. | Putative 3'(2'),5'-bisphosphate nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.459 |
| suhB | hisI | LHA_2205 | LHA_1401 | Inositol-1-monophosphatase. | Histidine biosynthesis bifunctional protein hisIE [Includes: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphatase]; In the N-terminal section; belongs to the PRA-CH family. | 0.595 |
| thyA | LHA_1984 | LHA_0193 | LHA_1984 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Putative 3'(2'),5'-bisphosphate nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.406 |
| topA | LHA_1984 | LHA_2889 | LHA_1984 | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] | Putative 3'(2'),5'-bisphosphate nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.514 |