STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LHA_2015Putative Restriction endonuclease, type I, R subunit/Type III, Res subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (702 aa)    
Predicted Functional Partners:
LHA_1205
Putative Acyltransferase 3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
    0.763
LHA_2022
Putative type I restriction enzyme HindVIIP M protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.742
LHA_2020
Restriction modification system, type I.
  
    0.494
msrA
Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
    0.471
LHA_1146
Homologs of previously reported genes of unknown function.
       0.461
LHA_1684
Putative mechanosensitive ion channel MscS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; transporter.
       0.461
LHA_1982
Helix-turn-helix type 11 domain protein.
       0.461
LHA_2018
Putative type I restriction enzyme HindVIIP R protein; Subunit R is required for both nuclease and ATPase activities, but not for modification.
       0.461
yjeF
Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...]
  
    0.432
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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