STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LHA_2022Putative type I restriction enzyme HindVIIP M protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (518 aa)    
Predicted Functional Partners:
LHA_2020
Restriction modification system, type I.
 
 
 0.999
LHA_2018
Putative type I restriction enzyme HindVIIP R protein; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.998
LHA_2023
Putative phage protein (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
  
    0.818
LHA_2019
Putative RNA-directed DNA polymerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.787
LHA_2021
Homologs of previously reported genes of unknown function.
       0.784
LHA_2017
Uncharacterized protein; Function of strongly homologous gene; putative enzyme;/product='putative helicase (fragment)'.
       0.773
LHA_2015
Putative Restriction endonuclease, type I, R subunit/Type III, Res subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.742
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]
    
 
 0.618
LHA_2025
Homologs of previously reported genes of unknown function.
  
    0.484
LHA_0148
Peptidase S24-like domain protein; Function of strongly homologous gene; enzyme.
  
  
 0.478
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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