Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LHA_2057FAD binding domain protein. (461 aa)    
Predicted Functional Partners:
LHA_2058
Homologs of previously reported genes of unknown function.
 
     0.951
kmo
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
  
    0.687
LHA_2088
Homologs of previously reported genes of unknown function.
  
     0.624
coxB
Cytochrome c oxidase subunit 2; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
   
 
 0.619
iraA
Small-molecule methyltransferase IraA; Function of strongly homologous gene; enzyme.
  
     0.560
LHA_1354
Putative coiled-coil protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
     0.554
LHA_2056
Putative O-methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
     0.519
LHA_2883
Homologs of previously reported genes of unknown function.
  
     0.512
LHA_2213
Flagellar protein FliJ.
  
     0.476
LHA_0403
Putative integral membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
     0.470
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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