STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metCCystathionine beta-lyase. (384 aa)    
Predicted Functional Partners:
cysK
Cysteine synthase; Function of strongly homologous gene; enzyme.
 
 0.997
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
 
 0.941
aatA
Aspartate aminotransferase A.
  
 
 0.925
ilvE
Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
   
 0.918
LHA_1352
Methionine--tRNA ligase; Function of strongly homologous gene; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
 0.914
trxB
Thioredoxin reductase.
   
 
 0.914
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.884
sdaA
L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
   
 
 0.837
LHA_2872
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
  
 
 0.826
pepN
Aminopeptidase N.
  
 
 0.815
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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