murA protein (Legionella hackeliae) - STRING interaction network

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murA

UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (422 aa)

Predicted Functional Partners:

murB

0.974

glmU

0.968

LHA_1949

0.906

vipB

0.905

murC

0.904

LHA_2096

0.903

lpxA

0.877

lpxA-2

0.877

yrbF

0.868

gtaB

0.867

Your Current Organism:

Legionella hackeliae

NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LHA_1949	glmU	LHA_1949	LHA_0184	UDP-N-acetylglucosamine 2-epimerase; Function of strongly homologous gene; enzyme; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.	Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.933
LHA_1949	gtaB	LHA_1949	LHA_2181	UDP-N-acetylglucosamine 2-epimerase; Function of strongly homologous gene; enzyme; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.	UTP--glucose-1-phosphate uridylyltransferase.	0.847
LHA_1949	lpxA	LHA_1949	LHA_0612	UDP-N-acetylglucosamine 2-epimerase; Function of strongly homologous gene; enzyme; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.	Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	0.802
LHA_1949	lpxA-2	LHA_1949	LHA_3169	UDP-N-acetylglucosamine 2-epimerase; Function of strongly homologous gene; enzyme; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.	Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	0.802
LHA_1949	murA	LHA_1949	LHA_2095	UDP-N-acetylglucosamine 2-epimerase; Function of strongly homologous gene; enzyme; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.906
LHA_1949	vipB	LHA_1949	LHA_1181	UDP-N-acetylglucosamine 2-epimerase; Function of strongly homologous gene; enzyme; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.	Vi polysaccharide biosynthesis protein vipB/tviC.	0.914
LHA_2096	murA	LHA_2096	LHA_2095	Homologs of previously reported genes of unknown function; Belongs to the BolA/IbaG family.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.903
LHA_2096	yrbF	LHA_2096	LHA_2101	Homologs of previously reported genes of unknown function; Belongs to the BolA/IbaG family.	Toluene transporter subunit: ATP-binding component of ABC superfamily; Function of strongly homologous gene; transporter.	0.869
glmU	LHA_1949	LHA_0184	LHA_1949	Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	UDP-N-acetylglucosamine 2-epimerase; Function of strongly homologous gene; enzyme; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.	0.933
glmU	gtaB	LHA_0184	LHA_2181	Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	UTP--glucose-1-phosphate uridylyltransferase.	0.889
glmU	lpxA	LHA_0184	LHA_0612	Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	0.834
glmU	lpxA-2	LHA_0184	LHA_3169	Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	0.834
glmU	murA	LHA_0184	LHA_2095	Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.968
glmU	murB	LHA_0184	LHA_2903	Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.	0.585
glmU	murC	LHA_0184	LHA_2904	Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.	0.570
glmU	vipB	LHA_0184	LHA_1181	Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Vi polysaccharide biosynthesis protein vipB/tviC.	0.914
gtaB	LHA_1949	LHA_2181	LHA_1949	UTP--glucose-1-phosphate uridylyltransferase.	UDP-N-acetylglucosamine 2-epimerase; Function of strongly homologous gene; enzyme; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.	0.847
gtaB	glmU	LHA_2181	LHA_0184	UTP--glucose-1-phosphate uridylyltransferase.	Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.889
gtaB	murA	LHA_2181	LHA_2095	UTP--glucose-1-phosphate uridylyltransferase.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.867
gtaB	vipB	LHA_2181	LHA_1181	UTP--glucose-1-phosphate uridylyltransferase.	Vi polysaccharide biosynthesis protein vipB/tviC.	0.873

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