STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LHA_2121Putative rhomboid family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (195 aa)    
Predicted Functional Partners:
xseA
Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
       0.852
LHA_2120
Peptidase; Function of strongly homologous gene; enzyme.
       0.852
amiC
N-acetylmuramoyl-L-alanine amidase.
   
   0.808
LHA_2116
Homologs of previously reported genes of unknown function.
  
    0.770
LHA_2117
Homologs of previously reported genes of unknown function.
       0.741
LHA_2118
Type I secretion outer membrane protein, TolC family precursor; Function of strongly homologous gene; transporter.
       0.741
LHA_2405
5-formyltetrahydrofolate cyclo-ligase; Function of strongly homologous gene; enzyme; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
  
  
 0.672
tatB
Sec-independent protein translocase TatB.
   
 
 0.606
tatA
Sec-independent protein translocase protein tatA/E homolog; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
   
 
 0.606
LHA_2465
Flavin containing monooxygenase.
       0.461
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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