korB protein (Legionella hackeliae) - STRING interaction network

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Score

korB

2-oxoglutarate ferredoxin oxidoreductase beta subunit. (324 aa)

Predicted Functional Partners:

korA

0.999

pta

0.965

pycB

0.959

LHA_2550

0.947

pykA

0.930

ppsA

0.923

sucD

0.923

sucC

0.923

acsA

0.916

icd

0.914

Your Current Organism:

Legionella hackeliae

NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LHA_2550	acsA	LHA_2550	LHA_0283	Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	0.950
LHA_2550	icd	LHA_2550	LHA_1241	Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.	Isocitrate dehydrogenase [NADP].	0.605
LHA_2550	korA	LHA_2550	LHA_2143	Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.	2-oxoglutarate synthase subunit korA; Function of strongly homologous gene; enzyme.	0.974
LHA_2550	korB	LHA_2550	LHA_2142	Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	0.947
LHA_2550	pta	LHA_2550	LHA_1604	Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.	Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.	0.936
LHA_2550	pycB	LHA_2550	LHA_0572	Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.	Pyruvate carboxylase subunit B.	0.626
LHA_2550	pykA	LHA_2550	LHA_0272	Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.488
LHA_2550	sucC	LHA_2550	LHA_2938	Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.	Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.874
LHA_2550	sucD	LHA_2550	LHA_2937	Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.	Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.865
acsA	LHA_2550	LHA_0283	LHA_2550	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.	0.950
acsA	korA	LHA_0283	LHA_2143	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	2-oxoglutarate synthase subunit korA; Function of strongly homologous gene; enzyme.	0.955
acsA	korB	LHA_0283	LHA_2142	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	0.916
acsA	pta	LHA_0283	LHA_1604	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.	0.928
acsA	pycB	LHA_0283	LHA_0572	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Pyruvate carboxylase subunit B.	0.848
acsA	sucC	LHA_0283	LHA_2938	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.836
acsA	sucD	LHA_0283	LHA_2937	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.826
icd	LHA_2550	LHA_1241	LHA_2550	Isocitrate dehydrogenase [NADP].	Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.	0.605
icd	korA	LHA_1241	LHA_2143	Isocitrate dehydrogenase [NADP].	2-oxoglutarate synthase subunit korA; Function of strongly homologous gene; enzyme.	0.959
icd	korB	LHA_1241	LHA_2142	Isocitrate dehydrogenase [NADP].	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	0.914
icd	sucC	LHA_1241	LHA_2938	Isocitrate dehydrogenase [NADP].	Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.936