era protein (Legionella hackeliae) - STRING interaction network

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[Homology]

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era

GTP-binding protein era homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (295 aa)

Predicted Functional Partners:

recO

0.931

ybeY

0.884

rpsG

0.828

rsmA

0.827

rpsP

0.826

rpsF

0.795

rpsI

0.795

fabD

0.791

rpsE

0.751

rpsO

0.734

Your Current Organism:

Legionella hackeliae

NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
era	fabD	LHA_2148	LHA_1781	GTP-binding protein era homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	Malonyl CoA-acyl carrier protein transacylase.	0.791
era	recO	LHA_2148	LHA_2147	GTP-binding protein era homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	DNA repair protein recO; Involved in DNA repair and RecF pathway recombination.	0.931
era	rpsE	LHA_2148	LHA_0356	GTP-binding protein era homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.	0.751
era	rpsF	LHA_2148	LHA_1549	GTP-binding protein era homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.795
era	rpsG	LHA_2148	LHA_0335	GTP-binding protein era homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.	0.828
era	rpsI	LHA_2148	LHA_2739	GTP-binding protein era homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.795
era	rpsO	LHA_2148	LHA_2973	GTP-binding protein era homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.	0.734
era	rpsP	LHA_2148	LHA_0453	GTP-binding protein era homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S16 (modular protein); Belongs to the bacterial ribosomal protein bS16 family.	0.826
era	rsmA	LHA_2148	LHA_3195	GTP-binding protein era homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	0.827
era	ybeY	LHA_2148	LHA_1859	GTP-binding protein era homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	Putative metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.884
fabD	era	LHA_1781	LHA_2148	Malonyl CoA-acyl carrier protein transacylase.	GTP-binding protein era homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	0.791
fabD	rpsE	LHA_1781	LHA_0356	Malonyl CoA-acyl carrier protein transacylase.	30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.	0.411
fabD	rpsF	LHA_1781	LHA_1549	Malonyl CoA-acyl carrier protein transacylase.	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.561
fabD	rpsG	LHA_1781	LHA_0335	Malonyl CoA-acyl carrier protein transacylase.	30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.	0.596
fabD	rpsI	LHA_1781	LHA_2739	Malonyl CoA-acyl carrier protein transacylase.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.450
fabD	rpsP	LHA_1781	LHA_0453	Malonyl CoA-acyl carrier protein transacylase.	30S ribosomal protein S16 (modular protein); Belongs to the bacterial ribosomal protein bS16 family.	0.855
fabD	rsmA	LHA_1781	LHA_3195	Malonyl CoA-acyl carrier protein transacylase.	Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	0.412
recO	era	LHA_2147	LHA_2148	DNA repair protein recO; Involved in DNA repair and RecF pathway recombination.	GTP-binding protein era homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	0.931
rpsE	era	LHA_0356	LHA_2148	30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.	GTP-binding protein era homolog; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	0.751
rpsE	fabD	LHA_0356	LHA_1781	30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.	Malonyl CoA-acyl carrier protein transacylase.	0.411

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