STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mrcAPenicillin-binding protein 1A [Includes: Penicillin-insensitive transglycosylase; Penicillin-sensitive transpeptidase]. (788 aa)    
Predicted Functional Partners:
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
  
 
 0.979
ftsI
Peptidoglycan synthase ftsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
  
 
 0.977
dacA
D-alanyl-D-alanine carboxypeptidase dacA; Belongs to the peptidase S11 family.
     
 0.927
LHA_2880
Serine-type D-Ala-D-Ala carboxypeptidase; Function of strongly homologous gene; enzyme.
     
 0.926
pbpC
Penicillin binding protein 1C, peptidoglycan biosynthesis.
  
  
0.923
LHA_3246
Homologs of previously reported genes of unknown function.
  
 
 
 0.894
LHA_2173
Protein of unknown function; No homology to any previously reported sequences.
       0.677
mrdB
Rod shape-determining protein rodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
   
 0.662
yceG
Putative conserved membrane associated protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
  
   
 0.621
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
   
 0.594
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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