STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mrcAPenicillin-binding protein 1A [Includes: Penicillin-insensitive transglycosylase; Penicillin-sensitive transpeptidase]. (788 aa)    
Predicted Functional Partners:
dacA
D-alanyl-D-alanine carboxypeptidase dacA; Belongs to the peptidase S11 family.
     
 0.925
pbpC
Penicillin binding protein 1C, peptidoglycan biosynthesis.
  
  
0.923
LHA_3246
Homologs of previously reported genes of unknown function.
  
 
 
 0.827
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
  
 
 
 0.738
ftsI
Peptidoglycan synthase ftsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
  
 
 
 0.702
mrdB
Rod shape-determining protein rodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
   
 0.664
rlpA-2
Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
 
 
 
 0.626
LHA_1927
Homologs of previously reported genes of unknown function.
 
  
 0.606
yceG
Putative conserved membrane associated protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
  
   
 0.563
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
   
 0.557
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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