Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LHA_2177Gnat family acetyltransferase. (156 aa)    
Predicted Functional Partners:
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 
 0.594
acsA-2
Acetoacetyl-coenzyme A synthetase [putative SET domain]; Function of strongly homologous gene; enzyme.
  
 
 0.594
icmP/dotM
Component of Dot/Icm secretion system. ATPase component; Homologs of previously reported genes of unknown function; structure.
  
     0.549
LHA_2566
Homologs of previously reported genes of unknown function.
  
     0.511
LHA_2647
Phage repressor.
  
     0.497
icmK/dotH
Component of the Dot/Icm secretion system; Function of strongly homologous gene; structure.
  
     0.458
LHA_2345
GCN5-related N-acetyltransferase; Function of strongly homologous gene; enzyme.
 
     0.436
LHA_1827
Histone deacetylase superfamily.
  
  
 0.433
LHA_2176
Homologs of previously reported genes of unknown function.
       0.400
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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