Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LHA_2268Putative Mitogen-activated protein kinase kinase kinase [STPK domain]; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (662 aa)    
Predicted Functional Partners:
LHA_0020
Serine/threonine-protein kinase; Function of strongly homologous gene; enzyme.
 
 
 0.790
cphA
Cyanophycin synthetase.
  
  
 0.779
LHA_0371
Serine/threonine-protein kinase; Function of strongly homologous gene; enzyme.
 
 
 0.775
LHA_0212
Putative Cyclin-dependent kinase [Serine/threonine-protein kinase-like domain]; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.753
amiC
N-acetylmuramoyl-L-alanine amidase.
     
 0.686
rsgA
Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
  
  
 0.678
LHA_1823
Conserved protein of unknown function [F-BOX/LEUCINE RICH REPEAT PROTEIN]; Homologs of previously reported genes of unknown function.
  
  
 0.643
LHA_0969
Sensory box histidine kinase/response regulator.
   
 
 0.639
LHA_2074
Putative sensory box histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
 
 0.639
LHA_2140
Putative sensory box sensor histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
 
 0.639
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
Server load: low (24%) [HD]