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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_2271Homologs of previously reported genes of unknown function. (305 aa)    
Predicted Functional Partners:
LHA_3255
Hyaluronan synthase; Function of strongly homologous gene; enzyme.
  
  
 0.638
icmE/dotG
Component of the Dot/Icm secretion system. Major component of a channel; Function of strongly homologous gene; structure.
  
     0.558
mscL
Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
       0.483
msrA
Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.459
LHA_2270
Protein of unknown function; No homology to any previously reported sequences.
       0.455
enhA
Enhanced entry protein EnhA.
  
     0.450
enhC
Enhanced entry protein EnhC-Beta-lactamase [Sel1-domain][Tetratricopeptide-like helical]; Function of strongly homologous gene; enzyme.
  
     0.446
LHA_2930
Homologs of previously reported genes of unknown function.
  
     0.443
dotA
Component of the Dot/Icm secretion system; Function of strongly homologous gene; membrane component.
  
     0.435
IcmF
IcmF protein; Function of strongly homologous gene; factor.
  
     0.430
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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