Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LHA_2280Bacterial surface antigen; Function of strongly homologous gene; membrane component. (549 aa)    
Predicted Functional Partners:
LHA_2281
Exported protein of unknown function; No homology to any previously reported sequences.
 
 
 0.998
hemB
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
       0.866
mutS
DNA mismatch repair protein mutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
       0.772
LHA_2283
Homologs of previously reported genes of unknown function.
       0.724
LHA_3127
Homologs of previously reported genes of unknown function.
  
     0.588
CinA
Competence-damage inducible protein CinA; Function of strongly homologous gene; cell process; Belongs to the CinA family.
       0.565
LHA_0799
Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
     0.453
LHA_1545
Putative ErfK/YbiS/YcfS/YnhG family protein precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   
 0.436
LHA_2441
Transcriptional regulator, MerR family (fragment).
 
     0.433
recX
Regulatory protein recX; Modulates RecA activity; Belongs to the RecX family.
 
     0.429
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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