Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LHA_2284Homologs of previously reported genes of unknown function. (480 aa)    
Predicted Functional Partners:
mip
Outer membrane protein MIP.
    
 
 0.821
bamA
Conserved exported protein of unknown function; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
    
 
 0.804
bamD
Conserved protein of unknown function; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
   
 
 0.804
LHA_2286
ATP-dependent DNA helicase (UvrD/Rep helicase); Belongs to the helicase family. UvrD subfamily.
 
     0.731
LHA_2285
Bifunctional aspartate kinase/diaminopimelate decarboxylase protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
    0.690
fadB
3-hydroxyacyl CoA dehydrogenase oxidoreductase protein/.
 
  
 0.514
LHA_2289
Putative ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
       0.461
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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