STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_2315Putative peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (515 aa)    
Predicted Functional Partners:
LHA_2314
Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...]
     
 0.556
LHA_2316
Protein of unknown function; No homology to any previously reported sequences.
       0.540
LHA_0521
Beta-lactamase domain-containing protein; No homology to any previously reported sequences;/product='fragment of protein of unknown function (part 2)'.
  
     0.498
LHA_2609
Putative Aspartate racemase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.477
LHA_1873
Protein with patatin domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
     0.463
LHA_0531
Methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology;/product='conserved protein of unknown function [Integrase, catalytic core, phage](fragment)'.
 
     0.457
LHA_2481
Chitinase; Function of strongly homologous gene; enzyme.
  
     0.455
legA
Conserved protein of unknown function [ankyrin repeat]; Homologs of previously reported genes of unknown function.
  
    0.443
LHA_2317
Putative amino acid ABC transporter, periplasmic binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.432
LHA_0504
Putative Methionyl-tRNA formyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.421
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.