Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LHA_2336Protein of unknown function [Tetratricopeptide region]; No homology to any previously reported sequences. (547 aa)    
Predicted Functional Partners:
LHA_2597
Protein of unknown function [coiled-coil domain]; No homology to any previously reported sequences.
   
 0.910
LHA_2334
Exported protein of unknown function; No homology to any previously reported sequences.
     
 0.744
LHA_2335
Putative family S53 non-peptidase homologue (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.741
LHA_1667
Homologs of previously reported genes of unknown function.
    
 
 0.613
LHA_3255
Hyaluronan synthase; Function of strongly homologous gene; enzyme.
  
 
 0.612
htpG
Chaperone protein htpG; Molecular chaperone. Has ATPase activity.
   
 0.594
dnaK
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.558
LHA_1827
Histone deacetylase superfamily.
    
  0.545
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.529
LHA_2333
Protein of unknown function; No homology to any previously reported sequences.
       0.498
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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