Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ahpCAlkyl hydroperoxide reductase, peroxiredoxin; Function of strongly homologous gene; enzyme. (179 aa)    
Predicted Functional Partners:
ahpD
Alkyl hydroperoxide reductase AhpD; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
  
 0.956
LHA_1667
Homologs of previously reported genes of unknown function.
  
 0.763
dnaK
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.697
trxB
Thioredoxin reductase.
  
 
 0.687
LHA_2838
Protein of unknown function; No homology to any previously reported sequences.
  
 
 0.662
LHA_2439
Putative Redoxin family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 0.659
sodC
Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 
 0.636
msrA
Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.610
LHA_0015
Thiol-disulfide oxidoreductase ResA.
  
 0.609
dsbE
Thiol:disulfide interchange protein DsbE.
  
 0.609
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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