Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
icmG/dotFComponent of the Dot/Icm secretion system; Function of strongly homologous gene; factor. (268 aa)    
Predicted Functional Partners:
icmE/dotG
Component of the Dot/Icm secretion system. Major component of a channel; Function of strongly homologous gene; structure.
   
 
 0.981
icmK/dotH
Component of the Dot/Icm secretion system; Function of strongly homologous gene; structure.
   
 
 0.975
IcmN/DotK
Component of the Dot/Icm secretion system. Lipoprotein of the OmpA protein family; Function of strongly homologous gene; lipoprotein.
   
 
 0.967
icmM/dotJ
Component of the Dot/Icm secretion system. Predicted inner membrane protein; Function of strongly homologous gene; membrane component.
     
 0.938
icmC/dotE
Component of the Dot/Icm secretion system; Function of strongly homologous gene; factor.
     
 0.895
icmL/dotI
Component of the Dot/Icm secretion system. Inner membrane protein; Function of strongly homologous gene; membrane component.
     
 0.890
icmD/DotP
Component of the Dot/Icm secretion system. Predicted innermembrane protein; Function of strongly homologous gene; membrane component.
   
 
 0.865
dotC
Component of the Dot/Icm secretion system. Lipoprotein; Function of strongly homologous gene; membrane component.
    
 
 0.845
dotD
Component of the Dot/Icm secretion system. Lipoprotein; Function of strongly homologous gene; structure.
    
 
 0.841
LHA_2712
IcmX protein.
    
 
 0.841
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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