Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
IcmN/DotKComponent of the Dot/Icm secretion system. Lipoprotein of the OmpA protein family; Function of strongly homologous gene; lipoprotein. (188 aa)    
Predicted Functional Partners:
icmK/dotH
Component of the Dot/Icm secretion system; Function of strongly homologous gene; structure.
   
 
 0.970
icmG/dotF
Component of the Dot/Icm secretion system; Function of strongly homologous gene; factor.
   
 
 0.967
LHA_2794
Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
   0.966
icmE/dotG
Component of the Dot/Icm secretion system. Major component of a channel; Function of strongly homologous gene; structure.
 
 
 0.944
icmM/dotJ
Component of the Dot/Icm secretion system. Predicted inner membrane protein; Function of strongly homologous gene; membrane component.
     
 0.890
icmL/dotI
Component of the Dot/Icm secretion system. Inner membrane protein; Function of strongly homologous gene; membrane component.
     
 0.885
mompS-3
Major outer membrane protein precursor; Function of strongly homologous gene; membrane component.
    
   0.885
icmC/dotE
Component of the Dot/Icm secretion system; Function of strongly homologous gene; factor.
     
 0.855
icmD/DotP
Component of the Dot/Icm secretion system. Predicted innermembrane protein; Function of strongly homologous gene; membrane component.
     
 0.824
LHA_3131
Putative Sodium-type flagellar protein motY precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; structure.
  
 
   0.805
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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