STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icmSComponent of Dot/Icm secretion system. Substrate recognition; Function of strongly homologous gene; factor. (114 aa)    
Predicted Functional Partners:
icmW
IcmW.
    
 
 0.921
icmO/dotL
Component of Dot/Icm secretion system. ATPase; Function of strongly homologous gene; enzyme.
   
 
 0.883
icmT
Component of the Dot/Icm secretion system; Function of strongly homologous gene; factor.
     
 0.806
IvgA
Virulence protein; Function of strongly homologous gene; putative factor.
    
 
 0.806
icmP/dotM
Component of Dot/Icm secretion system. ATPase component; Homologs of previously reported genes of unknown function; structure.
     
 0.763
LHA_2624
Conjugative coupling factor TraD.
   
 
 0.756
icmQ
Protein secretion of Dot/Icm secretion system; Function of strongly homologous gene; factor.
     
 0.633
dotB
Component of the Dot/Icm secretions system. ATPase; Function of strongly homologous gene; enzyme.
      
 0.568
LHA_2401
Protein of unknown function; No homology to any previously reported sequences.
       0.523
higA
Component of the Dot/Icm secretion system; Function experimentally demonstrated in the studied species; factor.
       0.515
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.