STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_2446Two-component sensor histidine kinase. (472 aa)    
Predicted Functional Partners:
LHA_2445
Diguanylate cyclase; No homology to any previously reported sequences;/product='fragment of protein of unknown function'.
 
 
 0.933
LHA_2447
Homologs of previously reported genes of unknown function.
 
   
 0.812
LHA_2140
Putative sensory box sensor histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.783
flgD
Flagellar basal-body rod modification protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein.
   
    0.769
LHA_0969
Sensory box histidine kinase/response regulator.
  
 
0.748
LHA_2074
Putative sensory box histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
0.748
LHA_2313
Sensory box histidine kinase/response regulator (fragment).
  
 
0.748
gacS/letS
Sensory box histidine kinase/response regulator.
 
 
 0.712
LHA_3063
Putative response regulator, PAS/GGDEF/EAL domain-containing protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.707
LHA_2634
Homologs of previously reported genes of unknown function.
  
     0.686
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.