Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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Experiments
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[Homology]
Score
LHA_2521Conserved protein of unknown function [TPR Domain]; Homologs of previously reported genes of unknown function. (376 aa)    
Predicted Functional Partners:
LHA_2597
Protein of unknown function [coiled-coil domain]; No homology to any previously reported sequences.
   
 0.913
legA
Conserved protein of unknown function [ankyrin repeat]; Homologs of previously reported genes of unknown function.
 
  0.811
LHA_3255
Hyaluronan synthase; Function of strongly homologous gene; enzyme.
  
 
 0.740
LHA_1152
Putative O-antigen ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.734
LHA_1738
Phosphoprotein phosphatase; Function of strongly homologous gene; enzyme.
 
 
 0.725
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
   0.702
LHA_2445
Diguanylate cyclase; No homology to any previously reported sequences;/product='fragment of protein of unknown function'.
   
 
 0.686
LHA_3063
Putative response regulator, PAS/GGDEF/EAL domain-containing protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
 
 0.686
LHA_2140
Putative sensory box sensor histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 
 0.675
LHA_3086
Phosphatidylcholine--sterol O-acyltransferase; Function of strongly homologous gene; enzyme.
  
     0.655
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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