Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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[Homology]
Score
LHA_2596Putative Heat shock protein, Hsp20 family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the small heat shock protein (HSP20) family. (173 aa)    
Predicted Functional Partners:
LHA_2815
Truncated low molecular weight heat shock protein; Belongs to the small heat shock protein (HSP20) family.
  
  
 
0.918
LHA_2601
Putative HSP20-like chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the small heat shock protein (HSP20) family.
  
  
 
0.900
clpA
ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family.
  
 
 0.686
clpB
Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.686
dnaK
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.476
LHA_2597
Protein of unknown function [coiled-coil domain]; No homology to any previously reported sequences.
  
 
 0.466
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 
 0.421
htpG
Chaperone protein htpG; Molecular chaperone. Has ATPase activity.
  
 
 0.415
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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