Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dotDComponent of the Dot/Icm secretion system. Lipoprotein; Function of strongly homologous gene; structure. (196 aa)    
Predicted Functional Partners:
dotC
Component of the Dot/Icm secretion system. Lipoprotein; Function of strongly homologous gene; membrane component.
   
 
 0.990
icmE/dotG
Component of the Dot/Icm secretion system. Major component of a channel; Function of strongly homologous gene; structure.
    
 
 0.945
dotB
Component of the Dot/Icm secretions system. ATPase; Function of strongly homologous gene; enzyme.
     
 0.914
icmK/dotH
Component of the Dot/Icm secretion system; Function of strongly homologous gene; structure.
    
 
 0.866
LHA_2700
Zinc protease (Peptidase, M16 family).
       0.866
LHA_2701
Zinc protease (Peptidase, M16 family).
       0.866
yhhF
Putative methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.
       0.866
icmG/dotF
Component of the Dot/Icm secretion system; Function of strongly homologous gene; factor.
    
 
 0.841
LHA_2794
Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
    
 
 0.790
IcmN/DotK
Component of the Dot/Icm secretion system. Lipoprotein of the OmpA protein family; Function of strongly homologous gene; lipoprotein.
    
   0.787
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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