Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dotBComponent of the Dot/Icm secretions system. ATPase; Function of strongly homologous gene; enzyme. (369 aa)    
Predicted Functional Partners:
dotC
Component of the Dot/Icm secretion system. Lipoprotein; Function of strongly homologous gene; membrane component.
 
   
 0.974
dotD
Component of the Dot/Icm secretion system. Lipoprotein; Function of strongly homologous gene; structure.
     
 0.914
pilD
Type 4 prepilin-like proteins leader peptide-processing enzyme [Includes: Leader peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
   
 0.894
pilC
Type 4 fimbrial assembly protein pilC.
 
  
 0.840
xcpS
General secretion pathway protein F.
 
  
 0.836
icmT
Component of the Dot/Icm secretion system; Function of strongly homologous gene; factor.
 
   
 0.802
LHA_2700
Zinc protease (Peptidase, M16 family).
       0.800
LHA_2701
Zinc protease (Peptidase, M16 family).
       0.800
yhhF
Putative methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.
       0.800
LHA_2167
Fimbrial assembly protein pilQ (fragment).
 
   
 0.784
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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