STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dotBComponent of the Dot/Icm secretions system. ATPase; Function of strongly homologous gene; enzyme. (369 aa)    
Predicted Functional Partners:
dotC
Component of the Dot/Icm secretion system. Lipoprotein; Function of strongly homologous gene; membrane component.
 
   
 0.921
pilD
Type 4 prepilin-like proteins leader peptide-processing enzyme [Includes: Leader peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
   
 0.854
pilC
Type 4 fimbrial assembly protein pilC.
 
  
 0.823
xcpS
General secretion pathway protein F.
 
  
 0.818
icmP/dotM
Component of Dot/Icm secretion system. ATPase component; Homologs of previously reported genes of unknown function; structure.
 
   
 0.802
dotD
Component of the Dot/Icm secretion system. Lipoprotein; Function of strongly homologous gene; structure.
     
 0.749
icmO/dotL
Component of Dot/Icm secretion system. ATPase; Function of strongly homologous gene; enzyme.
 
   
 0.701
icmT
Component of the Dot/Icm secretion system; Function of strongly homologous gene; factor.
 
   
 0.699
LHA_2700
Zinc protease (Peptidase, M16 family).
       0.698
LHA_2701
Zinc protease (Peptidase, M16 family).
       0.698
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.