STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dotAComponent of the Dot/Icm secretion system; Function of strongly homologous gene; membrane component. (679 aa)    
Predicted Functional Partners:
LHA_2708
DotA (fragment).
     0.981
icmV
Intracellular multiplication protein IcmV.
       0.786
AnkH
Substrate of the Dot/Icm secretion system [ankyrin repeat]; Function of strongly homologous gene; factor.
  
 
   0.782
icmJ
IcmJ protein.
 
     0.781
icmE/dotG
Component of the Dot/Icm secretion system. Major component of a channel; Function of strongly homologous gene; structure.
 
    0.781
icmL/dotI
Component of the Dot/Icm secretion system. Inner membrane protein; Function of strongly homologous gene; membrane component.
 
     0.776
dotC
Component of the Dot/Icm secretion system. Lipoprotein; Function of strongly homologous gene; membrane component.
 
     0.775
LHA_1417
Putative Enhanced entry protein EnhA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process.
  
     0.773
icmO/dotL
Component of Dot/Icm secretion system. ATPase; Function of strongly homologous gene; enzyme.
 
     0.773
icmT
Component of the Dot/Icm secretion system; Function of strongly homologous gene; factor.
  
     0.772
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
Server load: low (28%) [HD]