Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
icmVIntracellular multiplication protein IcmV. (152 aa)    
Predicted Functional Partners:
icmW
IcmW.
     
 0.907
LHA_2712
IcmX protein.
     
 0.898
LHA_2708
DotA (fragment).
       0.803
dotA
Component of the Dot/Icm secretion system; Function of strongly homologous gene; membrane component.
       0.803
icmM/dotJ
Component of the Dot/Icm secretion system. Predicted inner membrane protein; Function of strongly homologous gene; membrane component.
      
 0.703
IcmH/DotU
Component of the Dot/Icm secretion system; Function of strongly homologous gene; membrane component.
      
 0.696
IcmF
IcmF protein; Function of strongly homologous gene; factor.
      
 0.657
icmL/dotI
Component of the Dot/Icm secretion system. Inner membrane protein; Function of strongly homologous gene; membrane component.
      
 0.652
icmQ
Protein secretion of Dot/Icm secretion system; Function of strongly homologous gene; factor.
      
 0.639
tolC
Outer membrane protein TolC.
      
 0.418
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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