LHA_2712 protein (Legionella hackeliae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LHA_2712

IcmX protein. (480 aa)

Predicted Functional Partners:

icmW

0.948

icmE/dotG

0.903

icmV

0.898

icmG/dotF

0.841

LHA_2708

0.841

dotA

0.841

icmK/dotH

0.816

groL

0.649

dotB

0.649

dotC

0.647

Your Current Organism:

Legionella hackeliae

NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LHA_2708	LHA_2712	LHA_2708	LHA_2712	DotA (fragment).	IcmX protein.	0.841
LHA_2708	dotA	LHA_2708	LHA_2709	DotA (fragment).	Component of the Dot/Icm secretion system; Function of strongly homologous gene; membrane component.	0.980
LHA_2708	dotB	LHA_2708	LHA_2705	DotA (fragment).	Component of the Dot/Icm secretions system. ATPase; Function of strongly homologous gene; enzyme.	0.561
LHA_2708	dotC	LHA_2708	LHA_2704	DotA (fragment).	Component of the Dot/Icm secretion system. Lipoprotein; Function of strongly homologous gene; membrane component.	0.790
LHA_2708	icmE/dotG	LHA_2708	LHA_2389	DotA (fragment).	Component of the Dot/Icm secretion system. Major component of a channel; Function of strongly homologous gene; structure.	0.959
LHA_2708	icmG/dotF	LHA_2708	LHA_2388	DotA (fragment).	Component of the Dot/Icm secretion system; Function of strongly homologous gene; factor.	0.642
LHA_2708	icmK/dotH	LHA_2708	LHA_2390	DotA (fragment).	Component of the Dot/Icm secretion system; Function of strongly homologous gene; structure.	0.906
LHA_2708	icmV	LHA_2708	LHA_2710	DotA (fragment).	Intracellular multiplication protein IcmV.	0.803
LHA_2708	icmW	LHA_2708	LHA_2711	DotA (fragment).	IcmW.	0.629
LHA_2712	LHA_2708	LHA_2712	LHA_2708	IcmX protein.	DotA (fragment).	0.841
LHA_2712	dotA	LHA_2712	LHA_2709	IcmX protein.	Component of the Dot/Icm secretion system; Function of strongly homologous gene; membrane component.	0.841
LHA_2712	dotB	LHA_2712	LHA_2705	IcmX protein.	Component of the Dot/Icm secretions system. ATPase; Function of strongly homologous gene; enzyme.	0.649
LHA_2712	dotC	LHA_2712	LHA_2704	IcmX protein.	Component of the Dot/Icm secretion system. Lipoprotein; Function of strongly homologous gene; membrane component.	0.647
LHA_2712	groL	LHA_2712	LHA_2308	IcmX protein.	60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.649
LHA_2712	icmE/dotG	LHA_2712	LHA_2389	IcmX protein.	Component of the Dot/Icm secretion system. Major component of a channel; Function of strongly homologous gene; structure.	0.903
LHA_2712	icmG/dotF	LHA_2712	LHA_2388	IcmX protein.	Component of the Dot/Icm secretion system; Function of strongly homologous gene; factor.	0.841
LHA_2712	icmK/dotH	LHA_2712	LHA_2390	IcmX protein.	Component of the Dot/Icm secretion system; Function of strongly homologous gene; structure.	0.816
LHA_2712	icmV	LHA_2712	LHA_2710	IcmX protein.	Intracellular multiplication protein IcmV.	0.898
LHA_2712	icmW	LHA_2712	LHA_2711	IcmX protein.	IcmW.	0.948
dotA	LHA_2708	LHA_2709	LHA_2708	Component of the Dot/Icm secretion system; Function of strongly homologous gene; membrane component.	DotA (fragment).	0.980