STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_2719Protein of unknown function [Metallo-dependent hydrolase domain]; No homology to any previously reported sequences. (558 aa)    
Predicted Functional Partners:
LHA_2718
Homologs of previously reported genes of unknown function.
       0.718
LHA_2721
Exported protein of unknown function; No homology to any previously reported sequences.
  
   0.712
LHA_2720
Protein of unknown function; No homology to any previously reported sequences.
       0.705
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
  
 0.594
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.451
LHA_2630
Type IV secretory protein VirB4 component.
  
     0.416
fumB
Fumarate hydratase, class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
      
 0.412
LHA_2627
Homologs of previously reported genes of unknown function.
  
     0.410
LHA_2628
Membrane protein, Tfp pilus assembly, pilus retraction ATPase PilT.
  
     0.402
LHA_2629
Homologs of previously reported genes of unknown function.
  
     0.402
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.