STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemYProtoporphyrinogen IX and coproporphyrinogen III oxidase HemY. (392 aa)    
Predicted Functional Partners:
LHA_2772
Homologs of previously reported genes of unknown function.
 
  
 0.990
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
  
 0.902
hemD
Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
   
 0.899
LHA_2926
Conserved exported protein of unknown function; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
 
     0.771
LHA_3246
Homologs of previously reported genes of unknown function.
  
     0.621
LHA_0105
Homologs of previously reported genes of unknown function.
  
     0.557
LHA_2774
Homologs of previously reported genes of unknown function; Belongs to the pirin family.
       0.517
hemB
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
     
 0.514
LHA_1551
Homologs of previously reported genes of unknown function.
  
     0.511
LHA_1209
Homologs of previously reported genes of unknown function.
       0.461
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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