STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_2794Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (233 aa)    
Predicted Functional Partners:
IcmN/DotK
Component of the Dot/Icm secretion system. Lipoprotein of the OmpA protein family; Function of strongly homologous gene; lipoprotein.
  
 
   0.842
tolB
Protein tolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.835
icmE/dotG
Component of the Dot/Icm secretion system. Major component of a channel; Function of strongly homologous gene; structure.
 
   0.794
LHA_2795
Tryptophan/tyrosine permease family.
  
    0.738
kup
Putative potassium transport system protein kup 1; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.
       0.577
LHA_2796
Homologs of previously reported genes of unknown function.
  
    0.559
LHA_0609
Outer membrane protein OmpH; Belongs to the skp family.
  
 
 0.522
lolA
Outer-membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
 
 
 0.496
dotC
Component of the Dot/Icm secretion system. Lipoprotein; Function of strongly homologous gene; membrane component.
   
 
 0.480
icmK/dotH
Component of the Dot/Icm secretion system; Function of strongly homologous gene; structure.
   
   0.473
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.