Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
wrbA-2Flavoprotein wrbA; Belongs to the WrbA family. (201 aa)    
Predicted Functional Partners:
wrbA
Putative conserved flavoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
  
 
0.912
ubiE
Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
     
  0.900
LHA_2808
Arsenate reductase; Belongs to the ArsC family.
  
    0.885
xhtA
Endonuclease/exonuclease/phosphatase; Function of strongly homologous gene; enzyme.
       0.767
LHA_2806
Exodeoxyribonuclease III.
       0.767
dps
Ferritin and DNA-binding protein Dps; Function of strongly homologous gene; carrier; Belongs to the Dps family.
  
  
 0.756
LHA_2804
Homologs of previously reported genes of unknown function.
       0.711
rpmE
50S ribosomal protein L31; Binds the 23S rRNA.
  
    0.645
LHA_3040
Homologs of previously reported genes of unknown function.
   
    0.633
LHA_2643
Homologs of previously reported genes of unknown function.
   
    0.592
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
Server load: medium (60%) [HD]