LHA_2838 protein (Legionella hackeliae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LHA_2838

Protein of unknown function; No homology to any previously reported sequences. (58 aa)

Predicted Functional Partners:

LHA_1667

0.668

ahpC

0.662

LHA_3134

0.662

LHA_1744

0.639

trxA

0.639

trxA-2

0.639

msrA

0.624

LHA_2439

0.609

LHA_2837

0.527

LHA_0015

0.413

Your Current Organism:

Legionella hackeliae

NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LHA_0015	LHA_2838	LHA_0015	LHA_2838	Thiol-disulfide oxidoreductase ResA.	Protein of unknown function; No homology to any previously reported sequences.	0.413
LHA_0015	LHA_3134	LHA_0015	LHA_3134	Thiol-disulfide oxidoreductase ResA.	Putative peroxiredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	0.609
LHA_0015	ahpC	LHA_0015	LHA_2375	Thiol-disulfide oxidoreductase ResA.	Alkyl hydroperoxide reductase, peroxiredoxin; Function of strongly homologous gene; enzyme.	0.609
LHA_0015	msrA	LHA_0015	LHA_0099	Thiol-disulfide oxidoreductase ResA.	Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.934
LHA_1667	LHA_2439	LHA_1667	LHA_2439	Homologs of previously reported genes of unknown function.	Putative Redoxin family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	0.500
LHA_1667	LHA_2838	LHA_1667	LHA_2838	Homologs of previously reported genes of unknown function.	Protein of unknown function; No homology to any previously reported sequences.	0.668
LHA_1667	LHA_3134	LHA_1667	LHA_3134	Homologs of previously reported genes of unknown function.	Putative peroxiredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	0.763
LHA_1667	ahpC	LHA_1667	LHA_2375	Homologs of previously reported genes of unknown function.	Alkyl hydroperoxide reductase, peroxiredoxin; Function of strongly homologous gene; enzyme.	0.763
LHA_1667	msrA	LHA_1667	LHA_0099	Homologs of previously reported genes of unknown function.	Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.968
LHA_1744	LHA_2838	LHA_1744	LHA_2838	Exported protein of unknown function [TPR repeat]; No homology to any previously reported sequences.	Protein of unknown function; No homology to any previously reported sequences.	0.639
LHA_1744	LHA_3134	LHA_1744	LHA_3134	Exported protein of unknown function [TPR repeat]; No homology to any previously reported sequences.	Putative peroxiredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	0.431
LHA_1744	msrA	LHA_1744	LHA_0099	Exported protein of unknown function [TPR repeat]; No homology to any previously reported sequences.	Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.404
LHA_2439	LHA_1667	LHA_2439	LHA_1667	Putative Redoxin family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	Homologs of previously reported genes of unknown function.	0.500
LHA_2439	LHA_2838	LHA_2439	LHA_2838	Putative Redoxin family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	Protein of unknown function; No homology to any previously reported sequences.	0.609
LHA_2439	LHA_3134	LHA_2439	LHA_3134	Putative Redoxin family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	Putative peroxiredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	0.659
LHA_2439	ahpC	LHA_2439	LHA_2375	Putative Redoxin family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	Alkyl hydroperoxide reductase, peroxiredoxin; Function of strongly homologous gene; enzyme.	0.659
LHA_2439	msrA	LHA_2439	LHA_0099	Putative Redoxin family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.	Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.	0.980
LHA_2837	LHA_2838	LHA_2837	LHA_2838	Uncharacterized protein; Gene remnant;/product='fragment of Integrase/recombinase XerD, putative'.	Protein of unknown function; No homology to any previously reported sequences.	0.527
LHA_2838	LHA_0015	LHA_2838	LHA_0015	Protein of unknown function; No homology to any previously reported sequences.	Thiol-disulfide oxidoreductase ResA.	0.413
LHA_2838	LHA_1667	LHA_2838	LHA_1667	Protein of unknown function; No homology to any previously reported sequences.	Homologs of previously reported genes of unknown function.	0.668