Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LHA_2880Serine-type D-Ala-D-Ala carboxypeptidase; Function of strongly homologous gene; enzyme. (598 aa)    
Predicted Functional Partners:
dacA
D-alanyl-D-alanine carboxypeptidase dacA; Belongs to the peptidase S11 family.
     
 0.955
ftsI
Peptidoglycan synthase ftsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
     
 0.945
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
     
 0.926
mrcA
Penicillin-binding protein 1A [Includes: Penicillin-insensitive transglycosylase; Penicillin-sensitive transpeptidase].
     
 0.926
pbpC
Penicillin binding protein 1C, peptidoglycan biosynthesis.
   
 
 0.916
LHA_1302
Muramoyltetrapeptide carboxypeptidase; Function of strongly homologous gene; enzyme.
 
  
 0.719
LHA_2882
Protein of unknown function; No homology to any previously reported sequences.
       0.688
parB-2
Putative chromosome-partitioning protein parB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the ParB family.
       0.673
LHA_2883
Homologs of previously reported genes of unknown function.
 
     0.670
enhA
Enhanced entry protein EnhA.
  
  
 0.631
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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