Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LHA_2962Diguanylate cyclase; Function of strongly homologous gene; enzyme. (792 aa)    
Predicted Functional Partners:
LHA_0969
Sensory box histidine kinase/response regulator.
 
 0.965
LHA_2140
Putative sensory box sensor histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 0.965
LHA_2313
Sensory box histidine kinase/response regulator (fragment).
 
 0.965
LHA_2074
Putative sensory box histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 0.963
LHA_3063
Putative response regulator, PAS/GGDEF/EAL domain-containing protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
0.949
LHA_2445
Diguanylate cyclase; No homology to any previously reported sequences;/product='fragment of protein of unknown function'.
 
 
0.948
LHA_3196
Putative regulatory protein (GGDEF, PAS, PAC domains); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
0.932
LHA_2757
Protein of unknown function; No homology to any previously reported sequences.
  
 
 0.921
LHA_2758
Response regulator PleD [Includes: Diguanylate cyclase] (fragment).
 
 
 0.916
gacS/letS
Sensory box histidine kinase/response regulator.
 
 0.912
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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