STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHA_2968Zn-beta-lactamase (FEZ-1 protein); Function of strongly homologous gene; enzyme. (290 aa)    
Predicted Functional Partners:
kefC
Glutathione-regulated potassium-efflux system protein kefC; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.768
LHA_1119
Long-chain-fatty-acid--CoA ligase [Beta-ketoacyl synthase active site]; Function of strongly homologous gene; enzyme.
  
 
 0.703
LHA_1995
Beta-ketoacyl synthase (fragment).
  
 
 0.703
LHA_2609
Putative Aspartate racemase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.680
LHA_3205
AMP-dependent synthetase and ligase (fragment).
  
 
 0.599
LHA_0746
Type I phosphodiesterase/nucleotide pyrophosphatase.
  
    0.579
LHA_2073
6-deoxyerythronolide-B synthase; Function of strongly homologous gene; enzyme.
  
 
 0.565
LHA_0507
Protein of unknown function; No homology to any previously reported sequences; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.558
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
 
 0.548
LHA_1595
Homologs of previously reported genes of unknown function.
  
     0.470
Your Current Organism:
Legionella hackeliae
NCBI taxonomy Id: 449
Other names: ATCC 35250, CCUG 31232, CCUG 31232 A, CIP 103844, DSM 19214, JCM 7563, L. hackeliae, NCTC 11979, strain Lansing 2
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