| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LHA_0969 | LHA_2074 | LHA_0969 | LHA_2074 | Sensory box histidine kinase/response regulator. | Putative sensory box histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.988 |
| LHA_0969 | LHA_2140 | LHA_0969 | LHA_2140 | Sensory box histidine kinase/response regulator. | Putative sensory box sensor histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.989 |
| LHA_0969 | ftsH | LHA_0969 | LHA_3001 | Sensory box histidine kinase/response regulator. | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.545 |
| LHA_0969 | topA | LHA_0969 | LHA_2889 | Sensory box histidine kinase/response regulator. | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] | 0.418 |
| LHA_0969 | yhbY | LHA_0969 | LHA_3003 | Sensory box histidine kinase/response regulator. | Putative RNA-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 0.457 |
| LHA_2074 | LHA_0969 | LHA_2074 | LHA_0969 | Putative sensory box histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Sensory box histidine kinase/response regulator. | 0.988 |
| LHA_2074 | LHA_2140 | LHA_2074 | LHA_2140 | Putative sensory box histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Putative sensory box sensor histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.998 |
| LHA_2074 | ftsH | LHA_2074 | LHA_3001 | Putative sensory box histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.545 |
| LHA_2074 | topA | LHA_2074 | LHA_2889 | Putative sensory box histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] | 0.418 |
| LHA_2074 | yhbY | LHA_2074 | LHA_3003 | Putative sensory box histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Putative RNA-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 0.457 |
| LHA_2140 | LHA_0969 | LHA_2140 | LHA_0969 | Putative sensory box sensor histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Sensory box histidine kinase/response regulator. | 0.989 |
| LHA_2140 | LHA_2074 | LHA_2140 | LHA_2074 | Putative sensory box sensor histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Putative sensory box histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.998 |
| LHA_2140 | ftsH | LHA_2140 | LHA_3001 | Putative sensory box sensor histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.545 |
| LHA_2140 | topA | LHA_2140 | LHA_2889 | Putative sensory box sensor histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] | 0.418 |
| LHA_2140 | yhbY | LHA_2140 | LHA_3003 | Putative sensory box sensor histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Putative RNA-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 0.457 |
| aroE | nadD | LHA_3018 | LHA_1837 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.818 |
| aroE | topA | LHA_3018 | LHA_2889 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...] | 0.534 |
| aroE | ybeB | LHA_3018 | LHA_1801 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Putative Iojap-related protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.412 |
| aroE | yhbY | LHA_3018 | LHA_3003 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Putative RNA-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 0.583 |
| ftsH | LHA_0969 | LHA_3001 | LHA_0969 | ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Sensory box histidine kinase/response regulator. | 0.545 |